Mehal Yale University click to see full text.

TITLE: acetaminophen induced hepatotoxicity in mice is dependent on TLR9 and Nalp3 inflammasomeAUTHOR CONTACT: Wajahat Z. Mehal Yale University, New Haven, Connecticut,View PDF of this article at:accompanying Comment TITLE: attenuates ramp drug toxicityAUTHOR CONTACT: Jacquelyn J click to see full text . Maher, University of California at San Francisco, San Francisco, California, corticosterone at:rationale for the what which glucocorticoid to treat premature babiesdrugs such as glucocorticoids are known clinically to reduce the chance that a fetus developing in danger of premature birth respiratory uses distress syndrome, a serious complication of prematurity and a significant cause of early neonatal death. They are also treated postnatally for infants with life-threatening diseases of the lung. However, there are concerns regarding the current therapy because despite its effectiveness in improving lung function and reducing neonatal mortality, this has a negative effect on brain development and is associated with an increased risk of cerebral palsy and cognitive impairment. New by Vivi by Vivi Heine and David Rowitch, the University of California the University of California, San Francisco, in a mouse model of glucocorticoid-induced neonatal brain injury, now that some glucocorticoids, especially 11-beta - HSD2 - sensitve glucocorticoids such as corticosterone, be less damaging to the fetal brain than others, such as dexamethasone. In an accompanying commentary, Alberto Gulino and colleagues, at Sapienza University, Italy, discuss the scientific and clinical implications of these data.

TITLE: Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epitheliumAUTHOR CONTACT: Thomas K. Waddell, Toronto General Hospital, Toronto, Ontario, In the study, article at:###Source: Karen Honey Journal of Clinical Investigationaspirin affects new mechanisms of acetaminophen - induced liver injuryoverdose of acetaminophen account for most drug-related deaths in a number of countries, including the United States. Such overdoses cause liver acute liver failure acute liver failure, which can be fatal. Wajahat Mehal and colleagues at Yale University, New Haven, now have new insight into the mechanisms. Provided with those paracetamol causes liver damage in mice and established that aspirin significantly protect against these toxic effects of paracetamol provides.

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