Previous studies have shown that mice lacking the CaV3

Previous studies have shown that mice lacking the CaV3.1 T - type calcium channel sleep / wake sleep / wake activity. In this study, the researchers found that these mice were resistant to weight gain when fed a high fat diet read more . Consistent with these data, when normal-weight rodents a drug that specifically showed T - type calcium channels during their inactive phase they antagonized increased sleep and were protected from weight gain due to a high fat diet were administered. Also was fat mass. Same drug obese rodents where it reduces the body weight and fat mass. The authors conclude that the benefits of the drug to be a result of better alignment of feeding patterns and the circadian rhythms likely and that targeting T - type calcium channels could be a new avenue of research for the development of drugs to treat obesity offer.

In this study,ght Gain: a molecular linkIt seems to control a connection between sleep and weight, with some studies showing that sleep can weight gain and others that diet affects sleep increase. Victor Uebele and colleagues at Merck Research Laboratories, West Point, have now evidence for evidence of this correlation by the fact that T-type calcium channels regulate body weight to support maintenance and sleep in mice. These data suggest that sleep and circadian treatment approaches may be of benefit in the fight against obesity.

The authors of the study is Dr. Fontham, William Carpenter, research assistant professor of Health Policy and Management at the University of of North Carolina Gillings School of Global Public Health, James Mohler, Head of the Department of Urology at Roswell Park Cancer Institute, lead investigator of Consortium, and other scientists in these institutions. Supported health reforms Maps snapping Spotlight characteristics Emerge.